LangGraph
Stateful graph-based orchestration. Explicit state machine. Fine-grained control over agent flow. Best when you need deterministic, auditable agent behavior.
CrewAI
Multi-agent with role-based collaboration. Easy conceptual model (crew of agents with roles). Good for multi-agent scenarios where coordination patterns matter.
AutoGen
Microsoft’s framework. Multi-agent conversational patterns. Strong on chat-based coordination. Well-integrated with Azure OpenAI stack.
Selection
Deterministic, compliance-heavy: LangGraph. Multi-agent collaboration fit: CrewAI. Azure-first shop: AutoGen. Rapid prototyping: start with any; switch based on real patterns observed.